Nambala ya Orlistat Cas: 132539-06-1 Molecular Formula: C28H29NO
| Melting Point | 195-200 ° C |
| Kuchulukana | 1.4g/cm³ |
| kutentha kutentha | 2-8 ℃ |
| kusungunuka | osasungunuka m'madzi, osungunuka pang'ono mu Mowa, osungunuka mosavuta mu chloroform ndi methanol |
| kuwala ntchito | +71.6 (c=1.0, ethanol) |
| Maonekedwe | woyera kapena woyera crystalline ufa |
Olistat ndi yokhalitsa, yeniyeni ya m'mimba ya lipase inhibitor yomwe ingalepheretse hydrolysis ya triglycerides kukhala mafuta otsekemera amafuta aulere ndi monoacylglycerols, kuwalepheretsa kuti asatengeke, potero amachepetsa kudya kwa calorie ndikuwongolera kulemera.Ikagwiritsidwa ntchito ngati mankhwala osagwiritsidwa ntchito paokha, orlistat ndiyoyenera kuchiza odwala onenepa kwambiri kapena onenepa kwambiri (omwe ali ndi index ya ≥ 24 ndi kuwerengera pafupifupi kulemera / kutalika kwa 2).
Orlistat ndi mankhwala ochepetsa thupi, ogulitsidwa ngati Xenical.
Olistat ndi chochokera ku lipstatin.Lipstatin ndi mankhwala achilengedwe a pancrelipase inhibitor otalikirana ndi Streptomyces toxitricini Imagwira makamaka pamatumbo am'mimba.Ikhoza kulepheretsa ma enzyme omwe amafunikira m'mimba kuti agaye mafuta, kuphatikizapo pancreatic ester ndi chapamimba ester, ndi kuchepetsa kuyamwa kwa m'mimba ester ku mafuta kuti athandize kuchepetsa thupi, komabe amayenera kuphatikizidwa ndi masewera olimbitsa thupi ndi zakudya kuti achepetse thupi.
Mlingo wovomerezeka wa makapisozi a Olistat ndi makapisozi a 0.12g omwe amatengedwa ndi chakudya kapena mkati mwa ola limodzi mutatha kudya.Ngati pali chakudya chomwe sichinadyedwe kapena ngati chakudyacho chilibe mafuta, mankhwala amodzi akhoza kuchotsedwa.Kuchiza kwa kugwiritsa ntchito makapisozi a orlistat kwa nthawi yayitali, kuphatikiza kuwongolera kulemera ndi kusintha kwa zinthu zomwe zingayambitse chiopsezo, zitha kupitilira.Zakudya za wodwalayo ziyenera kukhala zopatsa thanzi, zopatsa mphamvu zochepa zama calorie.Pafupifupi 30% ya zakudya zopatsa mphamvu zimachokera ku mafuta, ndipo chakudyacho chiyenera kukhala ndi zipatso ndi ndiwo zamasamba.
