Nambala ya Cas: 21187-98-4 Chithunzi Chowonetsedwa cha Molecular Formula

Nambala ya Cas: 21187-98-4 Molecular Formula

Kufotokozera Kwachidule:

Nambala ya Cas: 21187-98-4

Dzina la Chemical:

Molecular formula: C15H21N3O3S

Mawu ofanana ndi mawu:BP;) -4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl) urea;1-(hexahydrocyclopenta(c)pyrrol-2(1h )-yl)-3-(p-tolylsulfonyl)-ure;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)urea;benzenesulfonamide,n-((((hexahydrocyclopenta() c)pyrrol-2(1h)-yl)amino)carbonyl;n-(4-methylbenzenesulfonyl)-n'-(3-azabicyclo(3.3.0)oct-3-yl)urea;Tetrabenzyl Voglibose HCl

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Kufotokozera Kwazinthu

Melting Point	163-169 ° C
Kuchulukana	1.2205 (kuyerekeza movutikira)
kutentha kutentha	M'mlengalenga, Kutentha kwa Zipinda 2-8 ° C
kusungunuka	methylene chloride: sungunuka
kuwala ntchito	N / A
Maonekedwe	Off-White Solid
Chiyero	≥98%

Kufotokozera

Ndi mankhwala apakamwa a antihyperglycemic omwe amagwiritsidwa ntchito pochiza matenda a shuga a mtundu II.Ndiwo gulu la sulfonylurea la insulin secretagogues, lomwe limalimbikitsa ma cell a pancreatic β kuti atulutse insulin.Amamangirira ku β cell sulfonyl urea receptor (SUR1), kutsekereza njira za potaziyamu za ATP.Chifukwa chake, potassium efflux imachepa kwambiri, zomwe zimapangitsa kuti ma cell a β awonongeke.Kenako mayendedwe a calcium omwe amadalira voltage mu cell β amakhala otseguka, zomwe zimapangitsa kuti kukhazikike kwa calmodulin, komwe kumabweretsa exocytosis ya insulin yokhala ndi ma secretory granules.Kafukufuku waposachedwa wawonetsanso kuti amatha kupititsa patsogolo anti-oxidant ndi nitric oxide-mediated vasodilation mu Type 2 shuga mellitus ndikuteteza maselo a pancreatic beta kuti asawonongeke ndi hydrogen peroxide.

kagwiritsidwe ntchito ndi mlingo wake

ndi mankhwala a hypoglycemic oral omwe amagwiritsidwa ntchito pochiza matenda a shuga osadalira insulini.Kuchiza matenda a shuga okhudzana ndi kunenepa kwambiri kapena matenda a mitsempha, kwa akuluakulu omwe ali ndi matenda a shuga a mtundu wa 2. Matenda a shuga ndi matenda aakulu (okhalitsa) omwe amakhudza momwe thupi lanu limasinthira. chakudya kukhala mphamvu.amachepetsa kuchuluka kwa shuga m'magazi polimbikitsa kutulutsa kwa insulin kuchokera ku ma β-cell a islets of Langerhans.