Nambala ya Cas: 171599-83-0 Molecular Formula: C 2 2 H 3 0 N 6 O 4 S·C 6 H 8 O 7 = 666.70
| Melting Point | 49-53 ° |
| Kuchulukana | 1.05g/cm³ |
| kutentha kutentha | malo ozizira, owuma komanso kupewa kukhudzana ndi kuwala kapena kutentha kwambiri |
| kusungunuka | Amasungunuka mosavuta mu ethanol, acetone, ether, benzene ndi methylene chloride, koma osasungunuka m'madzi. |
| kuwala ntchito | [α]D20 = +61.0° (mankhwala a ethanol) |
| Maonekedwe | ufa wonyezimira woyera mpaka wonyezimira wachikasu |
Panthawi yogonana, mitsempha ya parasympathetic, non adrenergic and non cholinergic nerve (NANC) mapeto ndi ma cell endothelial cell amatulutsa nitric oxide (NO) pansi pa nitric oxide synthase (NOS).M'mitsempha yamagazi, soluble guanylate cyclase (sGC) nthawi zambiri imayendetsedwa ndi NO, ndipo sGC imagwira ntchito pa guanosine triphosphate kupanga cGMP.CGMP mu corpus cavernosum ya mbolo imakhala ndi mphamvu ya vasodilator mwa kuchepetsa kuchuluka kwa Ca2 + m'maselo osalala a minofu ya corpus cavernosum, kuchititsa kupumula kwa maselo osalala a minofu ndi kuwonjezeka kwa magazi mkati mwa corpus cavernosum, kutsogolera. ku erection.Jinyang alkali amachepetsa kuchuluka kwa kuwonongeka kwa cGMP, potero kusunga mphamvu yopumula ya cGMP pa corpus cavernosum ya mbolo ndikuyambitsa penile erection.Mu vivo, cGMP imanyozedwa ndikusinthidwa ndi PDE5.
Ndiwoyenera kuchiza erectile dysfunction (ED) ya mbolo, ndiyothandiza pa vuto la erectile lomwe limadza chifukwa chogwiritsa ntchito mankhwala ochepetsa kupsinjika, antipsychotics, ndi antihypertensive mankhwala, komanso kulephera kwa erectile komwe kumachitika chifukwa cha opaleshoni kapena kuvulala.
Itha kupangidwa kukhala mapiritsi, mapiritsi, makapisozi olimba, makapisozi ofewa, ndipo angagwiritsidwe ntchito ngati vinyo wamankhwala, madzi amkamwa, khofi, ma granules, mapiritsi otafuna, lozenges, chingamu, ndi mitundu ina ya mlingo.Kwa akuluakulu, mlingo uyenera kukhala 10-100mg patsiku, womwe ukhoza kuwonjezeka kapena kuchepetsedwa malinga ndi momwe wogwiritsa ntchitoyo alili.Ndi bwino kumwa pamimba yopanda kanthu (makamaka kupewa kudya ndi mafuta ambiri), ndipo musamamwe mowa musanagwiritse ntchito Tiyi (kumwa sayenera kumwa nthawi yomweyo, zomwe sizikutanthauza kuti kumwa mowa nthawi yomweyo. nthawi imatha kuchepetsa kwambiri erectile ntchito ya Viagra).
Nthawi yogwira ntchito: Anthu ambiri amatenga ola limodzi kuti ayambe kugwira ntchito.Ndibwino kuti mutenge mankhwala pafupifupi ola la 1 musanayambe kugonana, ndipo zotsatira zake zimakhalapo kwa maola 48 mpaka 72, ndipo zina zimatha maola 116.
